Results for O75475

PNG SVG

Sequence

O75475 is from the genome.

The highlighted portions of sequence are where there is 75% agreement between all disorder pedictors.

>O75475
MTRDFKPGDLIFAKMKGYPHWPARVDEVPDGAVKPPTNKLPIFFFGTHETAFLGPKDIFPYSENKEKYGKPNKRKGFNEGLWEIDNNPKVKFSSQQAATKQSNASSDVEVEEKETSVSKEDTDHEEKASNEDVTKAVDITTPKAARRGRKRKAEKQVETEEAGVVTTATASVNLKVSPKRGRPAATEVKIPKPRGRPKMVKQPCPSESDIITEEDKSKKKGQEEKQPKKQPKKDEEGQKEEDKPRKEPDKKEGKKEVESKRKNLAKTGVTSTSDSEEEGDDQEGEKKRKGGRNFQTAHRRNMLKGQHEKEAADRKRKQEEQMETEQQNKDEGKKPEVKKVEKKRETSMDSRLQRIHAEIKNSLKIDNLDVNRCIEALDELASLQVTMQQAQKHTEMITTLKKIRRFKVSQVIMEKSTMLYNKFKNMFLVGEGDSVITQVLNKSLAEQRQHEEANKTKDQGKKGPNKKLEKEQTGSKTLNGGSDAQDGNQPQHNGESNEDSKDNHEASTKKKPSSEERETEISLKDSTLDN

View in source genome browser

UniProt Gene descriptions

UniProt Gene Name Gene Description
G3RJ84 PSIP1 Uncharacterized protein
H2QX09 ENSG00000164985 Uncharacterized protein
O75475 PSIP1 Transcriptional coactivator p75/p52

Disordered Regions

75% of predictor's agree:

Start End
65 79
87 351
441 530

By predictor:

Predictor Start End
VLXT 1 7
VSL2b 1 5
PrDOS 1 9
PV2 1 5
IUPred-S 1 8
Espritz-N 1 6
Espritz-X 1 7
PV2 9 10
PV2 17 18
PV2 20 23
IUPred-L 23 32
VLXT 28 31
Espritz-N 28 39
PV2 29 30
IUPred-S 29 29
PrDOS 30 37
VSL2b 31 33
PV2 32 34
IUPred-S 32 32
IUPred-L 39 39
PV2 53 53
IUPred-L 56 56
VSL2b 59 365
Espritz-X 59 347
PV2 60 61
Espritz-N 62 79
PV2 63 361
IUPred-L 63 82
IUPred-S 64 65
Espritz-D 65 295
PrDOS 68 79
IUPred-S 70 72
IUPred-S 79 81
IUPred-L 84 358
PrDOS 87 351
IUPred-S 88 88
Espritz-N 88 351
IUPred-S 92 158
VLXT 100 208
IUPred-S 171 345
VLXT 217 326
VLXT 332 359
IUPred-S 347 349
IUPred-L 360 361
VLXT 381 385
IUPred-L 381 400
PrDOS 387 389
VSL2b 388 394
PV2 388 388
PrDOS 390 391
VLXT 397 410
IUPred-L 423 423
Espritz-N 430 433
Espritz-X 430 530
PrDOS 433 530
VLXT 438 467
IUPred-L 438 530
PV2 440 530
VSL2b 441 530
Espritz-N 441 530
IUPred-S 446 530
Espritz-D 460 530
VLXT 477 530

SCOP Domain Regions

Hits with strong support:

Superfamily Name SFam ID SFam E-value Family Name Fam ID Fam E-value Region
Tudor/PWWP/MBT 63748 9.63e-32 PWWP domain 69250 0.00000836 3-127
HIV integrase-binding domain 140576 6.41e-30 HIV integrase-binding domain 140577 0.00000733 347-426

Hits with weaker support:

No weak SCOP hits found.

Pfam Domain Regions

Type Clan Family Name Description E-value Bitscore Start End
Domain CL0049 PF00855.12 PWWP PWWP domain 4.1e-18 65.3 5 87
Family No Clan PF11467.3 LEDGF Lens epithelium-derived growth factor (LEDGF) 1.4e-40 137.2 349 455

Post Translational Modification Sites

Locus Amino Acid Disordered PTM Type Sequence Context
6 K Yes UBIQUITYLATION __MTRDFkPGDLIFA
14 K Yes UBIQUITYLATION PGDLIFAkMkGyPHW
16 K Yes UBIQUITYLATION DLIFAkMkGyPHWPA
18 Y Yes PHOSPHORYLATION IFAkMkGyPHWPARV
34 K Yes UBIQUITYLATION EVPDGAVkPPTNKLP
62 S Yes PHOSPHORYLATION PKDIFPYsENKEKYG
75 K Yes SUMOYLATION YGKPNKRkGFNEGLW
75 K Yes UBIQUITYLATION YGKPNKRkGFNEGLW
94 S Yes PHOSPHORYLATION NPKVKFSsQQAATkQ
100 K Yes UBIQUITYLATION SsQQAATkQsNAssD
102 S Yes PHOSPHORYLATION QQAATkQsNAssDVE
105 S Yes PHOSPHORYLATION ATkQsNAssDVEVEE
106 S Yes PHOSPHORYLATION TkQsNAssDVEVEEK
115 T Yes PHOSPHORYLATION VEVEEKEtsVsKEDt
116 S Yes PHOSPHORYLATION EVEEKEtsVsKEDtD
118 S Yes PHOSPHORYLATION EEKEtsVsKEDtDHE
122 T Yes PHOSPHORYLATION tsVsKEDtDHEEKAs
129 S Yes PHOSPHORYLATION tDHEEKAsNEDVTkA
135 K Yes UBIQUITYLATION AsNEDVTkAVDIttP
140 T Yes PHOSPHORYLATION VTkAVDIttPKAARR
141 T Yes PHOSPHORYLATION TkAVDIttPKAARRG
166 T Yes PHOSPHORYLATION TEEAGVVttAtAsVN
167 T Yes PHOSPHORYLATION EEAGVVttAtAsVNL
169 T Yes PHOSPHORYLATION AGVVttAtAsVNLKV
171 S Yes PHOSPHORYLATION VVttAtAsVNLKVsP
177 S Yes PHOSPHORYLATION AsVNLKVsPKRGRPA
186 T Yes PHOSPHORYLATION KRGRPAAtEVKIPKP
206 S Yes PHOSPHORYLATION MVKQPCPsESDIItE
212 T Yes PHOSPHORYLATION PsESDIItEEDKSKK
220 K Yes ACETYLATION EEDKSKKkGQEEkQP
225 K Yes ACETYLATION KKkGQEEkQPkkQPk
228 K Yes ACETYLATION GQEEkQPkkQPkKDE
229 K Yes ACETYLATION QEEkQPkkQPkKDEE
232 K Yes ACETYLATION kQPkkQPkKDEEGQK
250 K Yes SUMOYLATION KPRKEPDkKEGkKEV
254 K Yes SUMOYLATION EPDkKEGkKEVESKR
267 T Yes PHOSPHORYLATION KRKNLAKtGVtstsD
270 T Yes PHOSPHORYLATION NLAKtGVtstsDsEE
271 S Yes PHOSPHORYLATION LAKtGVtstsDsEEE
272 T Yes PHOSPHORYLATION AKtGVtstsDsEEEG
273 S Yes PHOSPHORYLATION KtGVtstsDsEEEGD
275 S Yes PHOSPHORYLATION GVtstsDsEEEGDDQ
324 T Yes PHOSPHORYLATION KQEEQMEtEQQNKDE
346 T Yes PHOSPHORYLATION KVEKKREtsMDsRLQ
347 S Yes PHOSPHORYLATION VEKKREtsMDsRLQR
350 S Yes PHOSPHORYLATION KREtsMDsRLQRIHA
364 K Yes UBIQUITYLATION AEIKNSLkIDNLDVN
364 K Yes SUMOYLATION AEIKNSLkIDNLDVN
407 K Yes UBIQUITYLATION LKKIRRFkVSQVIME
415 K No UBIQUITYLATION VSQVIMEkSTMLYNk
422 K No UBIQUITYLATION kSTMLYNkFkNMFLV
424 K No UBIQUITYLATION TMLYNkFkNMFLVGE
434 S Yes PHOSPHORYLATION FLVGEGDsVItQVLN
437 T Yes PHOSPHORYLATION GEGDsVItQVLNksL
442 K Yes UBIQUITYLATION VItQVLNksLAEQRQ
443 S Yes PHOSPHORYLATION ItQVLNksLAEQRQH
461 K Yes ACETYLATION NKTKDQGkkGPNkKL
462 K Yes ACETYLATION KTKDQGkkGPNkKLE
466 K Yes ACETYLATION QGkkGPNkKLEKEQT
482 S Yes PHOSPHORYLATION SKTLNGGsDAQDGNQ
496 S Yes PHOSPHORYLATION QPQHNGEsNEDsKDN
500 S Yes PHOSPHORYLATION NGEsNEDsKDNHEAS
513 S Yes PHOSPHORYLATION ASTKKKPssEEREtE
514 S Yes PHOSPHORYLATION STKKKPssEEREtEI
519 T Yes PHOSPHORYLATION PssEEREtEIsLkDs
522 S Yes PHOSPHORYLATION EEREtEIsLkDstLD
524 K Yes UBIQUITYLATION REtEIsLkDstLDN_
526 S Yes PHOSPHORYLATION tEIsLkDstLDN___
527 T Yes PHOSPHORYLATION EIsLkDstLDN____

Discussion about protein O75475


comments powered by Disqus