Sequence
3349748 is from the genome.
The highlighted portions of sequence are where there is 75% agreement between all disorder pedictors.
>3349748
MELLRTITYQPAAGTKMCEQALGKACGGDSKKKRPQQPSEDGQSQAQVTPAAPHHHHHHSHSGPEISRIIVDPTTGKRYCRGKVLGKGGFAKCYEMTDLTNNKVYAAKIIPHSRVAKPHQREKIDKEIELHRILHHKHVVQFYHYFEDKENIYILLEYCSRRSMAHILKARKVLTEPEVRYYLRQIVSGLKYLHEQEILHRDLKLGNFFINEAMELKVGDFGLAARLEPLEHRRRTICGTPNYLSPEVLNKQGHGCESDIWALGCVMYTMLLGRPPFETTNLKETYRCIREARYTMPSSLLAPAKHLIASMLSKNPEDRPSLDDIIRHDFFLQGFTPDRLSSSCCHTVPDFHLSSPAKNFFKKAAAALFGGKKDKARYNDTHNKVSKEDEDIYKLRHDLKKTSITQQPSKHRTDEELQPPPTTFAKSGTSAVENKQQIGDAIRMIVRGTLGSCSSSSECLEDSTMGSVADTVARVLRGCLENMPEADCIPKEQLSTSFQWVTKWVDYSNKYGFGYQLSDHTVGVLFNNGAHMSLLPDKKTVHYYAELGQCSVFPATDAPEQFISQVTVLKYFSHYMEENLMDGGDLPSVTDIRRPRLYLLQWLKSDKALMMLFNDGTFQVNFYHDHTKIIICNQNEEYLLTYINEDRISTTFRLTTLLMSGCSLELKHRMEYALNMLLQRCN
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UniProt Gene descriptions
| UniProt |
Gene Name |
Gene Description |
| Q9R012 |
Plk2 |
Serum-inducible kinase |
Disordered Regions
75% of predictor's agree:
| Start |
End |
| 20 |
20 |
| 24 |
68 |
| 116 |
118 |
| 120 |
121 |
| 378 |
383 |
| 390 |
391 |
| 397 |
400 |
| 402 |
426 |
| 428 |
430 |
By predictor:
| Predictor |
Start |
End |
| VLXT |
1 |
1 |
| VSL2b |
1 |
68 |
| PrDOS |
1 |
74 |
| PV2 |
1 |
76 |
| IUPred-S |
1 |
7 |
| Espritz-N |
1 |
5 |
| Espritz-X |
1 |
74 |
| Espritz-N |
11 |
16 |
| Espritz-N |
18 |
76 |
| IUPred-L |
20 |
21 |
| IUPred-L |
23 |
68 |
| VLXT |
25 |
57 |
| IUPred-S |
26 |
70 |
| Espritz-D |
29 |
29 |
| Espritz-D |
33 |
33 |
| VLXT |
69 |
79 |
| PV2 |
80 |
80 |
| Espritz-N |
87 |
87 |
| VLXT |
110 |
130 |
| IUPred-L |
110 |
112 |
| PrDOS |
112 |
124 |
| Espritz-N |
112 |
121 |
| PV2 |
113 |
128 |
| VSL2b |
114 |
128 |
| IUPred-L |
116 |
118 |
| IUPred-S |
117 |
118 |
| IUPred-S |
120 |
121 |
| IUPred-L |
120 |
122 |
| IUPred-L |
127 |
127 |
| PV2 |
130 |
134 |
| VLXT |
166 |
179 |
| VLXT |
220 |
224 |
| PrDOS |
228 |
232 |
| PV2 |
229 |
229 |
| PV2 |
231 |
232 |
| PV2 |
235 |
235 |
| PV2 |
239 |
240 |
| Espritz-N |
241 |
242 |
| PV2 |
252 |
252 |
| VLXT |
285 |
293 |
| Espritz-N |
294 |
299 |
| VLXT |
297 |
317 |
| VSL2b |
297 |
305 |
| PV2 |
297 |
324 |
| VSL2b |
310 |
327 |
| Espritz-N |
312 |
324 |
| IUPred-L |
313 |
313 |
| PV2 |
326 |
326 |
| PV2 |
330 |
330 |
| PV2 |
332 |
332 |
| Espritz-N |
336 |
341 |
| PV2 |
337 |
340 |
| VSL2b |
338 |
344 |
| PrDOS |
342 |
497 |
| PV2 |
343 |
343 |
| VSL2b |
347 |
347 |
| VSL2b |
354 |
445 |
| PV2 |
356 |
356 |
| PV2 |
358 |
358 |
| PV2 |
360 |
360 |
| PV2 |
367 |
470 |
| Espritz-N |
368 |
391 |
| IUPred-L |
377 |
383 |
| VLXT |
378 |
383 |
| IUPred-S |
380 |
383 |
| IUPred-L |
386 |
387 |
| IUPred-S |
389 |
389 |
| IUPred-L |
389 |
392 |
| VLXT |
390 |
426 |
| IUPred-S |
392 |
392 |
| Espritz-N |
394 |
422 |
| IUPred-L |
396 |
430 |
| IUPred-S |
397 |
436 |
| Espritz-X |
402 |
430 |
| Espritz-N |
428 |
438 |
| VSL2b |
447 |
470 |
| VLXT |
452 |
467 |
| Espritz-N |
458 |
467 |
| VLXT |
479 |
489 |
| PV2 |
487 |
491 |
| VSL2b |
536 |
537 |
| PrDOS |
549 |
557 |
| VSL2b |
579 |
583 |
| PrDOS |
579 |
593 |
| Espritz-N |
581 |
592 |
| PV2 |
583 |
583 |
| PV2 |
589 |
589 |
| VLXT |
595 |
602 |
| PV2 |
669 |
669 |
| PV2 |
674 |
674 |
| PV2 |
677 |
677 |
| PrDOS |
678 |
682 |
| VSL2b |
679 |
682 |
| PV2 |
679 |
682 |
| IUPred-S |
682 |
682 |
SCOP Domain Regions
Hits with strong support:
| Superfamily Name |
SFam ID |
SFam E-value |
Family Name |
Fam ID |
Fam E-value |
Region |
| Polo-box domain |
82615 |
2.75e-40 |
|
|
|
470-587 |
| Polo-box domain |
82615 |
1.29e-26 |
|
|
|
591-679 |
| Protein kinase-like (PK-like) |
56112 |
6.74e-88 |
Protein kinases, catalytic subunit |
88854 |
0.0000103 |
77-356 |
Hits with weaker support:
No weak SCOP hits found.
Pfam Domain Regions
| Type |
Clan |
Family |
Name |
Description |
E-value |
Bitscore |
Start |
End |
| Domain |
CL0016 |
PF00069.20 |
Pkinase |
Protein kinase domain |
1.5e-69 |
234 |
79 |
331 |
| Family |
No Clan |
PF00659.13 |
POLO_box |
POLO box duplicated region |
2.7e-19 |
68.8 |
507 |
570 |
| Family |
No Clan |
PF00659.13 |
POLO_box |
POLO box duplicated region |
8.7e-17 |
60.8 |
603 |
674 |
Post Translational Modification Sites
| Locus |
Amino Acid |
Disordered |
PTM Type |
Sequence Context |
| 236 |
T |
No |
PHOSPHORYLATION |
PLEHRRRtICGTPNY |
| 393 |
Y |
Yes |
PHOSPHORYLATION |
SKEDEDIyKLRHDLK |
| 435 |
K |
Yes |
UBIQUITYLATION |
GTSAVENkQQIGDAI |