Trypanosoma brucei
Eukaryota; Euglenozoa; Kinetoplastida; Trypanosomatidae; Trypanosoma
Trypanosoma brucei is a species of parasitic kinetoplastid belonging to the genus Trypanosoma that is present in sub-Saharan Africa. Unlike other protozoan parasites that normally infect blood and tissue cells, it is exclusively extracellular and inhabits the blood plasma and body fluids. It causes deadly vector-borne diseases: African trypanosomiasis or sleeping sickness in humans, and animal trypanosomiasis or nagana in cattle and horses. It is a species complex grouped into three subspecies: T. b. brucei, T. b. gambiense and T. b. rhodesiense. The first is a parasite of non-human mammals and causes nagana, while the latter two are zoonotic infecting both humans and animals and cause African trypanosomiasis.
Sequence Statistics
No Sequences | 9895 |
---|---|
No Amino Acids | 4494306 |
Min Seq. Length | 25 |
Avg. Seq. Length | 454.200 |
Max Seq. Length | 12351 |
Seq. Length 1σ | 493.462 |
Disorder Prediction Statistics
Predictor | % Genome Disordered | % Genome Disordered in SCOP Domains | Avg. % of Seq. Disordered | Avg. % of Disordered Regions in SCOP Domains | Avg. % of Seq. Disordered and in SCOP Domains |
---|---|---|---|---|---|
VLXT | 34.239 | 4.900 | 32.591 | 17.198 | 5.003 |
VSL2b | 37.449 | 3.791 | 36.780 | 14.146 | 3.930 |
PrDOS | 39.869 | 3.474 | 39.063 | 11.653 | 3.383 |
PV2 | 43.816 | 4.916 | 48.331 | 14.825 | 4.943 |
IUPred-S | 16.819 | 0.813 | 17.464 | 7.765 | 0.967 |
IUPred-L | 19.850 | 1.025 | 21.920 | 12.382 | 1.383 |
Espritz-N | 28.230 | 2.660 | 26.720 | 12.999 | 2.527 |
Espritz-X | 15.509 | 0.624 | 17.439 | 5.786 | 0.782 |
Espritz-D | 5.125 | 0.243 | 27.185 | 5.097 | 2.358 |
SUPERFAMILY Domains
% Amino Acids with SCOP Assignment | % Sequences with SCOP Assignment | No of Domains | No of Superfamilies | No of Families | Avg. Family Size | Avg. Domain Length | Domain Pairs | Unique Domain Architectures |
---|---|---|---|---|---|---|---|---|
28 | 41 | 5729 | 679 | 383 | 8.4 | 454 | 459 | 1620 |