Trypanosoma brucei
Eukaryota; Euglenozoa; Kinetoplastida; Trypanosomatidae; Trypanosoma
Trypanosoma brucei is a species of parasitic kinetoplastid belonging to the genus Trypanosoma. This parasite is the cause of vector-borne diseases of vertebrate animals, including humans, carried by species of tsetse fly in sub-Saharan Africa. In humans T. brucei causes African trypanosomiasis, or sleeping sickness. In animals it causes animal trypanosomiasis, also called nagana in cattle and horses. T. brucei has traditionally been grouped into three subspecies: T. b. brucei, T. b. gambiense and T. b. rhodesiense. The first is a parasite of non-human vertebrates, while the latter two are known to be parasites of humans. Only rarely can the T. b. brucei infect a human.
Sequence Statistics
| No Sequences | 9895 |
|---|---|
| No Amino Acids | 4494306 |
| Min Seq. Length | 25 |
| Avg. Seq. Length | 454.200 |
| Max Seq. Length | 12351 |
| Seq. Length 1σ | 493.462 |
Disorder Prediction Statistics
| Predictor | % Genome Disordered | % Genome Disordered in SCOP Domains | Avg. % of Seq. Disordered | Avg. % of Disordered Regions in SCOP Domains | Avg. % of Seq. Disordered and in SCOP Domains |
|---|---|---|---|---|---|
| VLXT | 34.239 | 4.900 | 32.591 | 17.198 | 5.003 |
| VSL2b | 37.449 | 3.791 | 36.780 | 14.146 | 3.930 |
| PrDOS | 39.869 | 3.474 | 39.063 | 11.653 | 3.383 |
| PV2 | 43.816 | 4.916 | 48.331 | 14.825 | 4.943 |
| IUPred-S | 16.819 | 0.813 | 17.464 | 7.765 | 0.967 |
| IUPred-L | 19.850 | 1.025 | 21.920 | 12.382 | 1.383 |
| Espritz-N | 28.230 | 2.660 | 26.720 | 12.999 | 2.527 |
| Espritz-X | 15.509 | 0.624 | 17.439 | 5.786 | 0.782 |
| Espritz-D | 5.125 | 0.243 | 27.185 | 5.097 | 2.358 |
SUPERFAMILY Domains
| % Amino Acids with SCOP Assignment | % Sequences with SCOP Assignment | No of Domains | No of Superfamilies | No of Families | Avg. Family Size | Avg. Domain Length | Domain Pairs | Unique Domain Architectures |
|---|---|---|---|---|---|---|---|---|
| 28 | 41 | 5729 | 679 | 383 | 8.4 | 454 | 459 | 1620 |