Trypanosoma brucei is a species of parasitic kinetoplastid belonging to the genus Trypanosoma that is present in sub-Saharan Africa. Unlike other protozoan parasites that normally infect blood and tissue cells, it is exclusively extracellular and inhabits the blood plasma and body fluids. It causes deadly vector-borne diseases: African trypanosomiasis or sleeping sickness in humans, and animal trypanosomiasis or nagana in cattle and horses. It is a species complex grouped into three subspecies: T. b. brucei, T. b. gambiense and T. b. rhodesiense. The first is a parasite of non-human mammals and causes nagana, while the latter two are zoonotic infecting both humans and animals and cause African trypanosomiasis.

Sequence Statistics

No Sequences9895
No Amino Acids4494306
Min Seq. Length25
Avg. Seq. Length454.200
Max Seq. Length12351
Seq. Length 1σ493.462

Disorder Prediction Statistics

Predictor % Genome Disordered % Genome Disordered in SCOP Domains Avg. % of Seq. Disordered Avg. % of Disordered Regions in SCOP Domains Avg. % of Seq. Disordered and in SCOP Domains
VLXT 34.239 4.900 32.591 17.198 5.003
VSL2b 37.449 3.791 36.780 14.146 3.930
PrDOS 39.869 3.474 39.063 11.653 3.383
PV2 43.816 4.916 48.331 14.825 4.943
IUPred-S 16.819 0.813 17.464 7.765 0.967
IUPred-L 19.850 1.025 21.920 12.382 1.383
Espritz-N 28.230 2.660 26.720 12.999 2.527
Espritz-X 15.509 0.624 17.439 5.786 0.782
Espritz-D 5.125 0.243 27.185 5.097 2.358

SUPERFAMILY Domains

% Amino Acids with SCOP Assignment % Sequences with SCOP Assignment No of Domains No of Superfamilies No of Families Avg. Family Size Avg. Domain Length Domain Pairs Unique Domain Architectures
28 41 5729 679 383 8.4 454 459 1620

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