Candida parapsilosis
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; mitosporic Saccharomycetales; Candida
Candida parapsilosis is a fungal species of yeast that has become a significant cause of sepsis and of wound and tissue infections in immunocompromised people. Unlike Candida albicans and Candida tropicalis, C. parapsilosis is not an obligate human pathogen, having been isolated from nonhuman sources such as domestic animals, insects and soil. C. parapsilosis is also a normal human commensal and it is one of the fungi most frequently isolated from human hands. There are several risk factors that can contribute to C. parapsilosis colonization. Immunocompromised individuals and surgical patients, particularly those undergoing surgery of the gastrointestinal tract, are at high risk for infection with C. parapsilosis. There is currently no consensus on the treatment of invasive candidiasis caused by C. parapsilosis, although the therapeutic approach typically includes the removal of foreign bodies such as implanted prostheses and the administration of systemic antifungal therapy. amphotericin B and fluconazole are often used in the treatment of C. parapsilosis infection.
Sequence Statistics
| No Sequences | 5733 |
|---|---|
| No Amino Acids | 2924508 |
| Min Seq. Length | 43 |
| Avg. Seq. Length | 510.118 |
| Max Seq. Length | 4128 |
| Seq. Length 1σ | 349.502 |
Disorder Prediction Statistics
| Predictor | % Genome Disordered | % Genome Disordered in SCOP Domains | Avg. % of Seq. Disordered | Avg. % of Disordered Regions in SCOP Domains | Avg. % of Seq. Disordered and in SCOP Domains |
|---|---|---|---|---|---|
| VLXT | 29.147 | 5.631 | 28.807 | 27.445 | 6.246 |
| VSL2b | 39.344 | 6.104 | 39.044 | 24.769 | 6.951 |
| PrDOS | 39.256 | 4.590 | 38.463 | 19.439 | 5.050 |
| PV2 | 42.860 | 7.340 | 43.303 | 25.497 | 8.140 |
| IUPred-S | 20.446 | 1.215 | 19.870 | 13.186 | 1.558 |
| IUPred-L | 22.813 | 1.467 | 23.619 | 19.196 | 1.943 |
| Espritz-N | 29.537 | 3.726 | 28.076 | 22.304 | 3.994 |
| Espritz-X | 21.448 | 1.079 | 21.268 | 10.312 | 1.450 |
| Espritz-D | 7.540 | 0.359 | 22.393 | 7.083 | 3.007 |
SUPERFAMILY Domains
| % Amino Acids with SCOP Assignment | % Sequences with SCOP Assignment | No of Domains | No of Superfamilies | No of Families | Avg. Family Size | Avg. Domain Length | Domain Pairs | Unique Domain Architectures |
|---|---|---|---|---|---|---|---|---|
| 39 | 63 | 5170 | 769 | 583 | 6.7 | 510 | 521 | 1623 |