Schistosoma mansoni is a water-borne parasite of humans, and belongs to the group of blood flukes (Schistosoma). The adult lives in the blood vessels (mesenteric veins) near the human intestine. It causes intestinal schistosomiasis (similar to S. japonicum, S. mekongi, S. guineensis, and S. intercalatum). Clinical symptoms are caused by the eggs. As the leading cause of schistosomiasis in the world, it is the most prevalent parasite in humans. It is classified as a neglected tropical disease. As of 2021, the World Health Organization reports that 251.4 million people have schistosomiasis and most of it is due to S. mansoni. It is found in Africa, the Middle East, the Caribbean, Brazil, Venezuela and Suriname.

Sequence Statistics

No Sequences13191
No Amino Acids5893726
Min Seq. Length20
Avg. Seq. Length446.799
Max Seq. Length7660
Seq. Length 1σ482.064

Disorder Prediction Statistics

Predictor % Genome Disordered % Genome Disordered in SCOP Domains Avg. % of Seq. Disordered Avg. % of Disordered Regions in SCOP Domains Avg. % of Seq. Disordered and in SCOP Domains
VLXT 28.072 4.647 27.657 21.623 4.961
VSL2b 42.103 4.821 40.424 18.477 5.260
PrDOS 42.143 4.363 41.612 15.407 4.612
PV2 42.431 5.723 43.863 19.259 6.346
IUPred-S 16.857 0.936 17.602 9.910 1.238
IUPred-L 20.161 1.189 23.301 13.439 1.652
Espritz-N 27.812 2.870 25.299 16.340 2.762
Espritz-X 14.984 0.739 17.049 8.678 1.132
Espritz-D 4.655 0.565 46.265 11.085 7.135

SUPERFAMILY Domains

% Amino Acids with SCOP Assignment % Sequences with SCOP Assignment No of Domains No of Superfamilies No of Families Avg. Family Size Avg. Domain Length Domain Pairs Unique Domain Architectures
33 53 11383 900 673 12.6 447 847 2828

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