Sequence
3246830 is from the genome.
The highlighted portions of sequence are where there is 75% agreement between all disorder pedictors.
>3246830
MTQFLPPNLLALFAPRDPIPYLPPLEKLPHEKHHNQPYCGIAPYIREFEDPRDAPPPTRAETREERMERKRREKIERRQQEVETELKMWDPHNDPNAQGDAFKTLFVARVNYDTTESKLRREFEVYGPIKRIHMVYSKRSGKPRGYAFIEYEHERDMHSAYKHADGKKIDGRRVLVDVERGRTVKGWRPRRLGGGLGGTRRGGADVNIRHSGRDDTSRYDERPGPSPLPHRDRDRDRERERRERSRERDKERERRRSRSRDRRRRSRSRDKDERRRSRERSKDKDRDRKRRSSRSRERARRERERKEELRGGGGGGGGGSGGGGGGDMAEPSEAGDGAPDDGPPGELGPEGPDGPEEKGRDRDRERRRSHRSERERRRDRDRDRDREHKRGERGSERGRDEARGGGGSGQDNGLEGLGSDGRDMYMEAEGGDGYMAPENGYLMEAAPE
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UniProt Gene descriptions
| UniProt |
Gene Name |
Gene Description |
| A2RS68 |
Snrnp70 |
U1 small nuclear ribonucleoprotein polypeptide A, isoform CRA_a |
| Q62376 |
Snrnp70 |
U1 small nuclear ribonucleoprotein 70 kDa |
Disordered Regions
75% of predictor's agree:
| Start |
End |
| 50 |
91 |
| 180 |
180 |
| 186 |
448 |
By predictor:
| Predictor |
Start |
End |
| VLXT |
1 |
5 |
| VSL2b |
1 |
10 |
| PrDOS |
1 |
5 |
| PV2 |
1 |
14 |
| IUPred-S |
1 |
5 |
| Espritz-N |
1 |
5 |
| Espritz-X |
1 |
5 |
| PrDOS |
6 |
7 |
| IUPred-L |
7 |
7 |
| Espritz-N |
15 |
100 |
| PV2 |
16 |
98 |
| IUPred-L |
16 |
16 |
| VSL2b |
19 |
97 |
| VLXT |
20 |
24 |
| IUPred-L |
21 |
33 |
| IUPred-S |
33 |
34 |
| IUPred-L |
36 |
36 |
| IUPred-S |
39 |
39 |
| IUPred-L |
39 |
42 |
| IUPred-S |
44 |
79 |
| IUPred-L |
44 |
94 |
| Espritz-X |
49 |
80 |
| Espritz-D |
50 |
72 |
| PrDOS |
51 |
99 |
| VLXT |
52 |
91 |
| IUPred-S |
82 |
95 |
| IUPred-L |
100 |
101 |
| VSL2b |
119 |
119 |
| VLXT |
121 |
128 |
| PV2 |
128 |
128 |
| VLXT |
130 |
139 |
| PV2 |
133 |
176 |
| IUPred-L |
134 |
134 |
| IUPred-L |
136 |
137 |
| VSL2b |
138 |
143 |
| PrDOS |
138 |
142 |
| Espritz-N |
139 |
144 |
| IUPred-L |
145 |
175 |
| VSL2b |
152 |
172 |
| PrDOS |
161 |
162 |
| VLXT |
162 |
209 |
| IUPred-S |
162 |
164 |
| Espritz-N |
166 |
167 |
| PV2 |
178 |
448 |
| VSL2b |
179 |
448 |
| Espritz-X |
179 |
425 |
| IUPred-L |
180 |
180 |
| Espritz-N |
180 |
448 |
| IUPred-L |
184 |
184 |
| IUPred-L |
186 |
448 |
| IUPred-S |
189 |
239 |
| PrDOS |
191 |
448 |
| VLXT |
224 |
430 |
| Espritz-D |
231 |
231 |
| Espritz-D |
233 |
448 |
| IUPred-S |
260 |
260 |
| IUPred-S |
262 |
262 |
| IUPred-S |
265 |
269 |
| IUPred-S |
272 |
373 |
| IUPred-S |
379 |
380 |
| IUPred-S |
382 |
382 |
| IUPred-S |
384 |
432 |
| Espritz-X |
437 |
437 |
| IUPred-S |
439 |
448 |
| VLXT |
443 |
444 |
| Espritz-X |
444 |
448 |
| VLXT |
447 |
448 |
SCOP Domain Regions
Hits with strong support:
| Superfamily Name |
SFam ID |
SFam E-value |
Family Name |
Fam ID |
Fam E-value |
Region |
| RNA-binding domain, RBD |
54928 |
1.01e-29 |
|
|
|
88-204 |
Hits with weaker support:
No weak SCOP hits found.
Pfam Domain Regions
| Type |
Clan |
Family |
Name |
Description |
E-value |
Bitscore |
Start |
End |
| Family |
No Clan |
PF12220.3 |
U1snRNP70_N |
U1 small nuclear ribonucleoprotein of 70kDa MW N terminal |
7.1e-31 |
106.3 |
1 |
95 |
| Domain |
CL0221 |
PF00076.17 |
RRM_1 |
RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
3.4e-18 |
65 |
105 |
175 |
| Pfam-B |
No Clan |
PB012735 |
|
|
0.0000000000000086 |
55.5 |
157 |
203 |
| Pfam-B |
No Clan |
PB018364 |
|
|
0.0000011 |
28.2 |
205 |
325 |
| Pfam-B |
No Clan |
PB006309 |
|
|
0.000018 |
22.8 |
217 |
405 |
| Pfam-B |
No Clan |
PB009522 |
|
|
0.000036 |
25 |
229 |
329 |
Post Translational Modification Sites
| Locus |
Amino Acid |
Disordered |
PTM Type |
Sequence Context |
| 27 |
K |
Yes |
UBIQUITYLATION |
PYLPPLEkLPHEKHH |
| 38 |
Y |
Yes |
PHOSPHORYLATION |
EKHHNQPyCGIAPYI |
| 112 |
Y |
No |
PHOSPHORYLATION |
LFVARVNyDTTEskL |
| 117 |
S |
No |
PHOSPHORYLATION |
VNyDTTEskLRREFE |
| 118 |
K |
No |
UBIQUITYLATION |
NyDTTEskLRREFEV |
| 126 |
Y |
Yes |
PHOSPHORYLATION |
LRREFEVyGPIKRIH |
| 151 |
Y |
Yes |
PHOSPHORYLATION |
RGYAFIEyEHERDMH |
| 201 |
R |
Yes |
MONO-METHYLATION |
GGLGGTRrGGADVNI |
| 226 |
S |
Yes |
PHOSPHORYLATION |
YDERPGPsPLPHRDR |
| 266 |
S |
Yes |
PHOSPHORYLATION |
SRDRRRRsRsRDKDE |
| 268 |
S |
Yes |
PHOSPHORYLATION |
DRRRRsRsRDKDERR |
| 332 |
S |
Yes |
PHOSPHORYLATION |
GGDMAEPsEAGDGAP |
| 369 |
S |
Yes |
PHOSPHORYLATION |
RDRERRRsHRSERER |
| 408 |
S |
Yes |
PHOSPHORYLATION |
EARGGGGsGQDNGLE |
| 419 |
S |
Yes |
PHOSPHORYLATION |
NGLEGLGsDGRDMYM |