Sequence
3227375 is from the genome.
The highlighted portions of sequence are where there is 75% agreement between all disorder pedictors.
>3227375
MEDSMDMDMSPLRPQNYLFGCELKADKDYHFKVDNDENEHQLSLRTVSLGAGAKDELHIVEAEAMNYEGSPIKVTLATLKMSVQPTVSLGGFEITPPVVLRLKCGSGPVHISGQHLVAVEEDAESEDEDEEDVKLLGMSGKRSAPGGGNKVPQKKVKLDEDDEDDDEDDEDDEDDDDDDFDEEETEEKVPVKKSVRDTPAKNAQKSNQNGKDLKPSTPRSKGQESFKKQEKTPKTPKGPSSVEDIKAKMQASIEKGGSLPKVEAKFINYVKNCFRMTDQEAIQDLWQWRKSL
View in source genome browser
UniProt Gene descriptions
| UniProt |
Gene Name |
Gene Description |
| Q5SQB7 |
Npm1 |
Nucleophosmin 1 |
| Q61937 |
Npm1 |
Numatrin |
Disordered Regions
75% of predictor's agree:
| Start |
End |
| 1 |
8 |
| 114 |
114 |
| 116 |
259 |
By predictor:
| Predictor |
Start |
End |
| VLXT |
1 |
13 |
| VSL2b |
1 |
16 |
| PrDOS |
1 |
15 |
| PV2 |
1 |
18 |
| IUPred-S |
1 |
9 |
| IUPred-L |
1 |
7 |
| Espritz-N |
1 |
14 |
| Espritz-X |
1 |
9 |
| PV2 |
20 |
21 |
| PV2 |
28 |
34 |
| IUPred-L |
30 |
30 |
| VSL2b |
32 |
41 |
| IUPred-L |
32 |
32 |
| PrDOS |
33 |
37 |
| IUPred-L |
34 |
36 |
| PV2 |
37 |
37 |
| Espritz-N |
37 |
37 |
| PV2 |
39 |
41 |
| VLXT |
41 |
59 |
| IUPred-L |
42 |
47 |
| PrDOS |
53 |
55 |
| PV2 |
55 |
55 |
| IUPred-L |
60 |
60 |
| PrDOS |
61 |
72 |
| IUPred-L |
62 |
62 |
| PV2 |
65 |
68 |
| IUPred-L |
75 |
75 |
| VLXT |
77 |
78 |
| PV2 |
81 |
84 |
| PrDOS |
84 |
91 |
| Espritz-N |
85 |
93 |
| IUPred-L |
86 |
88 |
| PV2 |
89 |
90 |
| PV2 |
100 |
104 |
| IUPred-L |
103 |
105 |
| PV2 |
106 |
259 |
| Espritz-X |
106 |
248 |
| Espritz-N |
107 |
111 |
| IUPred-L |
111 |
261 |
| VLXT |
114 |
228 |
| VSL2b |
114 |
259 |
| Espritz-N |
114 |
114 |
| IUPred-S |
115 |
249 |
| PrDOS |
116 |
260 |
| Espritz-N |
120 |
260 |
| Espritz-D |
191 |
265 |
| IUPred-L |
285 |
286 |
| VLXT |
289 |
289 |
| VSL2b |
289 |
292 |
| PV2 |
289 |
292 |
| IUPred-S |
289 |
292 |
| PrDOS |
290 |
292 |
| Espritz-X |
290 |
292 |
| VLXT |
292 |
292 |
SCOP Domain Regions
Hits with strong support:
| Superfamily Name |
SFam ID |
SFam E-value |
Family Name |
Fam ID |
Fam E-value |
Region |
| Nucleoplasmin-like core domain |
69203 |
3.01e-44 |
Nucleoplasmin-like core domain |
69204 |
0.0000037 |
12-117 |
Hits with weaker support:
No weak SCOP hits found.
Pfam Domain Regions
| Type |
Clan |
Family |
Name |
Description |
E-value |
Bitscore |
Start |
End |
| Family |
No Clan |
PF03066.10 |
Nucleoplasmin |
Nucleoplasmin |
3.7e-55 |
185.5 |
13 |
195 |
Post Translational Modification Sites
| Locus |
Amino Acid |
Disordered |
PTM Type |
Sequence Context |
| 4 |
S |
Yes |
PHOSPHORYLATION |
____MEDsMDMDMsP |
| 10 |
S |
Yes |
PHOSPHORYLATION |
DsMDMDMsPLRPQNy |
| 17 |
Y |
Yes |
PHOSPHORYLATION |
sPLRPQNyLFGCELK |
| 27 |
K |
No |
ACETYLATION |
GCELKADkDyHFkVD |
| 27 |
K |
No |
UBIQUITYLATION |
GCELKADkDyHFkVD |
| 29 |
Y |
Yes |
PHOSPHORYLATION |
ELKADkDyHFkVDND |
| 32 |
K |
Yes |
ACETYLATION |
ADkDyHFkVDNDENE |
| 32 |
K |
Yes |
UBIQUITYLATION |
ADkDyHFkVDNDENE |
| 43 |
S |
Yes |
PHOSPHORYLATION |
DENEHQLsLRTVSLG |
| 54 |
K |
Yes |
UBIQUITYLATION |
VSLGAGAkDELHIVE |
| 67 |
Y |
Yes |
PHOSPHORYLATION |
VEAEAMNyEGsPIKV |
| 70 |
S |
Yes |
PHOSPHORYLATION |
EAMNyEGsPIKVtLA |
| 75 |
T |
Yes |
PHOSPHORYLATION |
EGsPIKVtLATLKMs |
| 82 |
S |
Yes |
PHOSPHORYLATION |
tLATLKMsVQPTVSL |
| 95 |
T |
No |
PHOSPHORYLATION |
SLGGFEItPPVVLRL |
| 106 |
S |
Yes |
PHOSPHORYLATION |
VLRLKCGsGPVHIsG |
| 112 |
S |
Yes |
PHOSPHORYLATION |
GsGPVHIsGQHLVAV |
| 125 |
S |
Yes |
PHOSPHORYLATION |
AVEEDAEsEDEDEED |
| 139 |
S |
Yes |
PHOSPHORYLATION |
DVKLLGMsGkRsAPG |
| 141 |
K |
Yes |
ACETYLATION |
KLLGMsGkRsAPGGG |
| 141 |
K |
Yes |
UBIQUITYLATION |
KLLGMsGkRsAPGGG |
| 143 |
S |
Yes |
PHOSPHORYLATION |
LGMsGkRsAPGGGNk |
| 150 |
K |
Yes |
ACETYLATION |
sAPGGGNkVPQkkVK |
| 154 |
K |
Yes |
UBIQUITYLATION |
GGNkVPQkkVKLDED |
| 154 |
K |
Yes |
ACETYLATION |
GGNkVPQkkVKLDED |
| 155 |
K |
Yes |
ACETYLATION |
GNkVPQkkVKLDEDD |
| 185 |
T |
Yes |
PHOSPHORYLATION |
DDFDEEEtEEKVPVK |
| 194 |
S |
Yes |
PHOSPHORYLATION |
EKVPVKKsVRdtPAK |
| 198 |
T |
Yes |
PHOSPHORYLATION |
VKKsVRdtPAKNAQK |
| 211 |
K |
Yes |
ACETYLATION |
QKSNQNGkDLKPstP |
| 216 |
S |
Yes |
PHOSPHORYLATION |
NGkDLKPstPRSkGQ |
| 217 |
T |
Yes |
PHOSPHORYLATION |
GkDLKPstPRSkGQE |
| 221 |
K |
Yes |
ACETYLATION |
KPstPRSkGQEsFkk |
| 225 |
S |
Yes |
PHOSPHORYLATION |
PRSkGQEsFkkQEKt |
| 227 |
K |
Yes |
ACETYLATION |
SkGQEsFkkQEKtPK |
| 228 |
K |
Yes |
ACETYLATION |
kGQEsFkkQEKtPKt |
| 232 |
T |
Yes |
PHOSPHORYLATION |
sFkkQEKtPKtPkGP |
| 235 |
T |
Yes |
PHOSPHORYLATION |
kQEKtPKtPkGPssV |
| 237 |
K |
Yes |
UBIQUITYLATION |
EKtPKtPkGPssVED |
| 240 |
S |
Yes |
PHOSPHORYLATION |
PKtPkGPssVEDIkA |
| 241 |
S |
Yes |
PHOSPHORYLATION |
KtPkGPssVEDIkAk |
| 246 |
K |
Yes |
UBIQUITYLATION |
PssVEDIkAkMQAsI |
| 248 |
K |
Yes |
UBIQUITYLATION |
sVEDIkAkMQAsIEk |
| 252 |
S |
Yes |
PHOSPHORYLATION |
IkAkMQAsIEkGGsL |
| 255 |
K |
Yes |
UBIQUITYLATION |
kMQAsIEkGGsLPkV |
| 255 |
K |
Yes |
ACETYLATION |
kMQAsIEkGGsLPkV |
| 258 |
S |
Yes |
PHOSPHORYLATION |
AsIEkGGsLPkVEAk |
| 261 |
K |
Yes |
UBIQUITYLATION |
EkGGsLPkVEAkFIN |
| 265 |
K |
Yes |
UBIQUITYLATION |
sLPkVEAkFINYVkN |
| 265 |
K |
Yes |
ACETYLATION |
sLPkVEAkFINYVkN |
| 271 |
K |
No |
ACETYLATION |
AkFINYVkNCFRMTD |
| 271 |
K |
No |
UBIQUITYLATION |
AkFINYVkNCFRMTD |