Results for 3219512

PNG SVG

Sequence

3219512 is from the genome.

The highlighted portions of sequence are where there is 75% agreement between all disorder pedictors.

>3219512
MQGNTCHRMSYHPGRGCPRGRGGHGARPSAPAFRPQNLRLLHPQQPPAQYQYEPPSAPSSSYSNSQAPSFMPPRPDFVPYPPPAAPSAQGPLPPCPVRPPYPNHQMRHPFPVPPCFPPMPPPMPCPNNPPASGAPPGQGTFPFMVPPPSMPHPPPPPVMPQQVNYQYPPGYSHSFPPPGFNSYQNNSSSFPPSANSSSTPHFRHLPPYSLPKAQNERRSPERLKHYDDHRHRDHSHGRGERHRSLERRERGRSPERRRPESRYRSDYDRGRTPPPRHRSYERSRERDRERHRHREARRSPSLERSYKKEYKRSGRSYALPVAPEPAGCTPELPGEMIKTTESWAPPPENVNHRSPSREKKRARWEEEKDRWSDSQGSGKEKNYTSIKEKEAEEVPPEKTEEEEEELLKPVWIRCTHSESYYSSDPMDQVGDSTVVGTSRLRDLYDKFEEELGNRQEKAKAARPPWEPPKTKLDEDLESSSESECETDDDSTCSSSSDSEVFDVIAEIKRKKAHPDRLHDELWYNDPGQMNDGPLCKCSAKARRTGIRHSIYPGEEAIKPCRPMTNNAGRLFHYRITVSPPTNFLTDRPTVIEYDDHEYIFEGFSMFAHAPLTNIPLCKVIRFNIDYTIHFIEEMMPENFCVKGLELFSLFLFRDILELYDWNLKGPLFEDSPPCCPRFHFMPRFVRFLPDGGKEVLSMHQILLYLLRCSKALVPEEEIANMLQWEELEWQKYAEECKGMIVTNPGTKPSSVRIDQLDREQFNPEVITFPIIVHFGIRPAQLSYAGDPQYQKLWKSYVKLRHLLANSPKVKQTDKQKLAQREEALQKIRQKNTMRREVTVELSSQGFWKTGIRSDVCQHAMMLPVLTHHIRYHQCLMHLDKLIGYTFQDRCLLQLAMTHPSHHLNFGMNPDHARNSLSNCGIRQPKYGDRKVHHMHMRKKGINTLINIMSRLGQDDPTPSRINHNERLEFLGDAVVEFLTSVHLYYLFPSLEEGGLATYRTAIVQNQHLAMLAKKLELDRFMLYAHGPDLCRESDLRHAMANCFEALIGAVYLEGSLEEAKQLFGRLLFNDPDLREVWLNYPLHPLQLQEPNTDRQLIETSPVLQKLTEFEEAIGVIFTHVRLLARAFTLRTVGFNHLTLGHNQRMEFLGDSIMQLVATEYLFIHFPDHHEGHLTLLRSSLVNNRTQAKVAEELGMQEYAITNDKTKRPVALRTKTLADLLESFIAALYIDKDLEYVHTFMNVCFFPRLKEFILNQDWNDPKSQLQQCCLTLRTEGKEPDIPLYKTLQTVGPSHARTYTVAVYFKGERIGCGKGPSIQQAEMGAAMDALEKYNFPQMAHQKRFIERKYRQELKEMRWEREHQEREPEEAEDIKK

View in source genome browser

UniProt Gene descriptions

UniProt	Gene Name	Gene Description
Q5HZJ0	Drosha	Ribonuclease III

Disordered Regions

75% of predictor's agree:

Start	End
1	104
106	113
117	409
424	433
443	443
445	493
495	495
810	813
829	829
1353	1373

By predictor:

Predictor	Start	End
VSL2b	1	434
PrDOS	1	409
PV2	1	439
IUPred-S	1	86
IUPred-L	1	104
Espritz-N	1	502
Espritz-X	1	95
Espritz-D	1	448
VLXT	2	29
VLXT	38	104
IUPred-S	89	92
IUPred-S	96	99
IUPred-L	106	113
VLXT	117	169
IUPred-L	117	409
Espritz-X	119	403
IUPred-S	127	149
IUPred-S	152	165
IUPred-S	167	172
IUPred-S	176	311
VLXT	186	192
VLXT	201	206
VLXT	209	376
IUPred-S	314	318
IUPred-S	321	404
VLXT	394	407
IUPred-L	418	492
IUPred-S	423	425
PrDOS	424	433
VLXT	425	430
IUPred-S	427	427
IUPred-S	432	434
VSL2b	437	439
VSL2b	441	516
PV2	441	504
VLXT	443	519
IUPred-S	446	448
Espritz-X	447	495
IUPred-S	451	452
IUPred-S	454	497
PrDOS	455	512
IUPred-L	495	495
IUPred-L	503	505
PV2	507	516
Espritz-N	507	549
IUPred-L	516	523
PV2	518	518
PV2	520	521
PV2	524	535
IUPred-S	524	524
IUPred-L	534	534
VSL2b	538	541
PV2	538	549
VLXT	541	561
PV2	552	552
VSL2b	553	556
Espritz-N	553	554
PV2	556	556
PV2	558	563
Espritz-N	561	567
PV2	565	567
PV2	581	585
Espritz-N	608	612
PV2	634	636
PV2	639	639
Espritz-N	664	671
PrDOS	668	672
PV2	670	670
PV2	677	677
PV2	679	679
VLXT	713	717
PV2	732	732
PV2	739	745
Espritz-N	741	763
VSL2b	744	751
VLXT	745	754
PV2	748	751
IUPred-S	751	755
IUPred-L	752	754
VLXT	799	836
PV2	800	838
PrDOS	802	836
VSL2b	805	838
Espritz-N	807	813
IUPred-S	810	817
IUPred-L	810	829
IUPred-S	820	823
IUPred-S	829	829
Espritz-N	829	831
Espritz-N	899	916
PrDOS	901	939
VSL2b	902	920
IUPred-L	903	909
PV2	904	941
IUPred-S	909	909
IUPred-L	914	914
IUPred-S	916	935
IUPred-L	916	919
VLXT	918	921
VSL2b	922	941
VLXT	924	938
Espritz-N	925	925
IUPred-L	932	932
IUPred-S	937	938
PrDOS	940	941
PV2	943	943
PrDOS	946	965
IUPred-S	947	947
PV2	948	949
IUPred-S	949	949
Espritz-N	949	962
VLXT	950	951
VSL2b	952	963
PV2	952	963
IUPred-L	955	958
IUPred-S	956	959
IUPred-L	962	962
PrDOS	1026	1037
VSL2b	1032	1032
PrDOS	1084	1101
VSL2b	1087	1094
PV2	1087	1096
VLXT	1088	1110
PrDOS	1135	1144
VLXT	1184	1196
PV2	1184	1186
VSL2b	1190	1190
PV2	1190	1190
VLXT	1200	1213
PrDOS	1202	1213
Espritz-N	1202	1206
VSL2b	1206	1206
PV2	1229	1229
PV2	1233	1233
Espritz-N	1255	1262
PV2	1261	1261
PV2	1265	1266
PV2	1268	1268
IUPred-L	1268	1268
PV2	1272	1279
PrDOS	1274	1277
VSL2b	1275	1279
Espritz-N	1276	1276
VLXT	1282	1287
IUPred-L	1282	1285
Espritz-N	1289	1293
PrDOS	1309	1373
VLXT	1315	1325
VSL2b	1316	1319
PV2	1320	1321
PV2	1324	1325
VSL2b	1330	1373
PV2	1332	1334
PV2	1336	1373
VLXT	1342	1373
Espritz-D	1344	1373
Espritz-N	1351	1373
IUPred-L	1353	1373
Espritz-X	1354	1373
IUPred-S	1359	1359
IUPred-S	1365	1373

SCOP Domain Regions

Hits with strong support:

Superfamily Name	SFam ID	SFam E-value	Region
RNase III domain-like	69065	7.85e-41	1100-1259
dsRNA-binding domain-like	54768	4.47e-16	1248-1335
RNase III domain-like	69065	2.79e-37	872-901,959-1073

Hits with weaker support:

No weak SCOP hits found.

Pfam Domain Regions

Type	Clan	Family	Name	Description	E-value	Bitscore	Start	End
Pfam-B	No Clan	PB009928			8.299999999999999e-41	139.3	264	393
Pfam-B	No Clan	PB009829			6.6e-55	183.5	400	489
Pfam-B	No Clan	PB000297			3.4e-33	115.9	445	724
Pfam-B	No Clan	PB010554			1.7e-159	528.7	510	757
Pfam-B	No Clan	PB001970			1.3000000000000001e-30	107.9	565	658
Pfam-B	No Clan	PB009703			1.9e-27	94.9	759	795
Family	CL0539	PF14622.1			5.3e-24	84.6	957	1071
Family	CL0539	PF00636.21	Ribonuclease_3	Ribonuclease III domain	3.2e-21	75.8	1143	1232
Domain	CL0196	PF00035.20	dsrm	Double-stranded RNA binding motif	0.00000000000009	51.8	1260	1331

View in Pfam

Post Translational Modification Sites

Locus	Amino Acid	Disordered	PTM Type	Sequence Context
299	S	Yes	PHOSPHORYLATION	RHREARRsPsLERsY
301	S	Yes	PHOSPHORYLATION	REARRsPsLERsYKK
305	S	Yes	PHOSPHORYLATION	RsPsLERsYKKEYKR

View at PhosphoSitePlus