Results for 3204273

PNG SVG

Sequence

3204273 is from the genome.

The highlighted portions of sequence are where there is 75% agreement between all disorder pedictors.

>3204273
MSVNVNRSVSDQFYRYKMPRLIAKVEGKGNGIKTVIVNMVDVAKALNRPPTYPTKYFGCELGAQTQFDVKNDRYIVNGSHEANKLQDMLDGFIKKFVLCPECENPETDLHVNPKKQTIGNSCKACGYRGMLDTHHKLCTFILKNPPENSDSGTGKKEKEKKNRKGKDKENGSVSSSETPPPPPPPNEINPPPHTMEEEEDDDWGEDTTEEAQRRRMDEISDHAKVLTLSDDLERTIEERVNILFDFVKKKKEEGVIDSSDKEIVAEAERLDVKAMGPLVLTEVLFNEKIREQIKKYRRHFLRFCHNNKKAQRYLLHGLECVVAMHQAQLISKIPHILKEMYDADLLEEEVIISWSEKASKKYVSKELAKEIRVKAEPFIKWLKEAEEESSGGEEEDEDENIEVVYSKAASVPKVETVKSDNKDDDIDIDAI

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UniProt Gene descriptions

UniProt	Gene Name	Gene Description
P55010	EIF5	Eukaryotic translation initiation factor 5

Disordered Regions

75% of predictor's agree:

Start	End
144	221
227	228
230	230
386	401
415	430

By predictor:

Predictor	Start	End
VSL2b	1	8
PrDOS	1	13
PV2	1	8
IUPred-S	1	6
Espritz-N	1	10
Espritz-X	1	8
PV2	64	68
IUPred-L	80	80
VSL2b	82	82
VSL2b	105	115
IUPred-L	107	115
PV2	109	115
Espritz-N	114	232
PV2	117	117
PV2	119	119
PV2	121	122
PV2	126	128
Espritz-X	126	221
VSL2b	132	239
PV2	132	132
PV2	138	230
IUPred-L	138	224
PrDOS	144	270
IUPred-S	149	216
VLXT	152	221
VLXT	225	232
IUPred-L	227	228
IUPred-L	230	230
VSL2b	248	264
Espritz-N	249	261
PV2	251	251
PV2	253	259
IUPred-L	257	258
VLXT	259	281
IUPred-L	260	260
PV2	264	264
PV2	266	266
Espritz-N	271	275
VLXT	285	303
PV2	333	333
VSL2b	355	431
PV2	355	431
PrDOS	358	359
PrDOS	362	363
Espritz-D	380	431
Espritz-X	383	431
PrDOS	384	431
Espritz-N	384	401
VLXT	386	403
IUPred-S	386	404
IUPred-L	386	387
IUPred-L	389	399
IUPred-L	401	401
IUPred-S	406	406
Espritz-N	406	431
IUPred-S	416	416
IUPred-L	416	416
VLXT	417	429
IUPred-S	418	418
IUPred-L	418	419
IUPred-L	422	422
IUPred-S	424	431
IUPred-L	425	425
IUPred-L	428	430

SCOP Domain Regions

Hits with strong support:

Superfamily Name	SFam ID	SFam E-value	Region
ARM repeat	48371	1.87e-28	237-386
Translation initiation factor 2 beta, aIF2beta, N-terminal domain	100966	4.32e-26	3-99
Zinc-binding domain of translation initiation factor 2 beta	75689	0.00000863	96-130

Hits with weaker support:

No weak SCOP hits found.

Pfam Domain Regions

Type	Clan	Family	Name	Description	E-value	Bitscore	Start	End
Family	No Clan	PF01873.12	eIF-5_eIF-2B	Domain found in IF2B/IF5	2.8e-46	156.2	1	130
Pfam-B	No Clan	PB001559			0.00069	18.9	271	430
Family	CL0020	PF02020.13	W2	eIF4-gamma/eIF5/eIF2-epsilon	1.2e-24	86	308	399

View in Pfam

Post Translational Modification Sites

Locus	Amino Acid	Disordered	PTM Type	Sequence Context
8	S	Yes	PHOSPHORYLATION	MSVNVNRsVsDQFYR
10	S	Yes	PHOSPHORYLATION	VNVNRsVsDQFYRyK
16	Y	No	PHOSPHORYLATION	VsDQFYRyKMPRLIA
28	K	Yes	ACETYLATION	LIAKVEGkGNGIkTV
33	K	No	ACETYLATION	EGkGNGIkTVIVNMV
55	K	No	UBIQUITYLATION	RPPTYPTkYFGCELG
55	K	No	ACETYLATION	RPPTYPTkYFGCELG
149	S	Yes	PHOSPHORYLATION	LKNPPENsDsGTGKK
151	S	Yes	PHOSPHORYLATION	NPPENsDsGTGKKEK
175	S	Yes	PHOSPHORYLATION	KENGSVSssETPPPP
176	S	Yes	PHOSPHORYLATION	ENGSVSssETPPPPP
207	T	Yes	PHOSPHORYLATION	DDDWGEDttEEAQRR
208	T	Yes	PHOSPHORYLATION	DDWGEDttEEAQRRR
227	T	Yes	PHOSPHORYLATION	SDHAKVLtLsDDLER
229	S	Yes	PHOSPHORYLATION	HAKVLtLsDDLERTI
288	K	Yes	UBIQUITYLATION	TEVLFNEkIREQIKK
362	Y	Yes	PHOSPHORYLATION	SEKASKKyVSKELAK
389	S	Yes	PHOSPHORYLATION	LKEAEEEssGGEEED
390	S	Yes	PHOSPHORYLATION	KEAEEEssGGEEEDE
405	Y	Yes	PHOSPHORYLATION	DENIEVVysKAAsVP
406	S	Yes	PHOSPHORYLATION	ENIEVVysKAAsVPK
410	S	Yes	PHOSPHORYLATION	VVysKAAsVPKVETV
419	S	Yes	PHOSPHORYLATION	PKVETVKsDNKDDDI

View at PhosphoSitePlus