Sequence
3177908 is from the genome.
The highlighted portions of sequence are where there is 75% agreement between all disorder pedictors.
>3177908
MGNGESQLSSVPAQKLGWFIQEYLKPYEECQTLIDEMVNTICDVLQEPEQFPLVQGVAIGGSYGRKTVLRGNSDGTLVLFFSDLKQFQDQKRSQRDILDKTGDKLKFCLFTKWLKNNFEIQKSLDGFTIQVFTKNQRISFEVLAAFNALSLNDNPSPWIYRELKRSLDKTNASPGEFAVCFTELQQKFFDNRPGKLKDLILLIKHWHQQCQKKIKDLPSLSPYALELLTVYAWEQGCRKDNFDIAEGVRTVLELIKCQEKLCIYWMVNYNFEDETIRNILLHQLQSARPVILDPVDPTNNVSGDKICWQWLKKEAQTWLTSPNLDNELPAPSWNVLPAPLFTTPGHLLDKFIKEFLQPNKCFLEQIDSAVNIIRTFLKENCFRQSTAKIQIVRGGSTAKGTALKTGSDADLVVFHNSLKSYTSQKNERHKIVKEIHEQLKAFWREKEEELEVSFEPPKWKAPRVLSFSLKSKVLNESVSFDVLPAFNALGQLSSGSTPSPEVYAGLIDLYKSSDLPGGEFSTCFTVLQRNFIRSRPTKLKDLIRLVKHWYKECERKLKPKGSLPPKYALELLTIYAWEQGSGVPDFDTAEGFRTVLELVTQYQQLCIFWKVNYNFEDETVRKFLLSQLQKTRPVILDPAEPTGDVGGGDRWCWHLLAKEAKEWLSSPCFKDGTGNPIPPWKVPTMQTPGSCGARIHPIVNEMFSSRSHRILNNNSKRNF
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UniProt Gene descriptions
| UniProt |
Gene Name |
Gene Description |
| P29728 |
OAS2 |
p69 OAS / p71 OAS |
Disordered Regions
75% of predictor's agree:
By predictor:
| Predictor |
Start |
End |
| VLXT |
1 |
10 |
| VSL2b |
1 |
10 |
| PrDOS |
1 |
12 |
| PV2 |
1 |
11 |
| IUPred-S |
1 |
8 |
| IUPred-L |
1 |
4 |
| Espritz-N |
1 |
16 |
| Espritz-X |
1 |
13 |
| VLXT |
40 |
55 |
| PV2 |
84 |
84 |
| VSL2b |
86 |
101 |
| PV2 |
87 |
90 |
| VLXT |
90 |
101 |
| PV2 |
92 |
93 |
| Espritz-N |
92 |
92 |
| Espritz-X |
93 |
93 |
| PV2 |
95 |
96 |
| PV2 |
105 |
105 |
| VLXT |
161 |
168 |
| VSL2b |
167 |
172 |
| PV2 |
167 |
167 |
| PV2 |
170 |
173 |
| Espritz-N |
170 |
172 |
| PrDOS |
171 |
175 |
| PrDOS |
212 |
221 |
| VSL2b |
213 |
217 |
| Espritz-N |
289 |
302 |
| PV2 |
290 |
290 |
| VLXT |
291 |
295 |
| PV2 |
293 |
293 |
| PV2 |
297 |
298 |
| PV2 |
317 |
320 |
| Espritz-N |
322 |
333 |
| PV2 |
324 |
327 |
| VSL2b |
325 |
327 |
| PV2 |
332 |
332 |
| PV2 |
334 |
334 |
| PV2 |
336 |
336 |
| VLXT |
393 |
400 |
| VSL2b |
398 |
404 |
| PV2 |
398 |
404 |
| VSL2b |
419 |
435 |
| PV2 |
421 |
421 |
| PV2 |
423 |
429 |
| PV2 |
431 |
435 |
| VSL2b |
440 |
477 |
| PV2 |
440 |
467 |
| Espritz-N |
445 |
451 |
| PrDOS |
447 |
454 |
| Espritz-N |
456 |
458 |
| VSL2b |
491 |
500 |
| Espritz-N |
491 |
499 |
| VLXT |
492 |
505 |
| PV2 |
494 |
495 |
| PV2 |
497 |
499 |
| PrDOS |
515 |
516 |
| PV2 |
515 |
516 |
| Espritz-N |
515 |
517 |
| VSL2b |
516 |
516 |
| PV2 |
518 |
519 |
| VLXT |
534 |
556 |
| PV2 |
547 |
547 |
| VSL2b |
555 |
564 |
| PrDOS |
555 |
565 |
| Espritz-N |
557 |
565 |
| PV2 |
558 |
562 |
| PV2 |
565 |
567 |
| PV2 |
570 |
570 |
| Espritz-N |
581 |
582 |
| PrDOS |
627 |
631 |
| PV2 |
630 |
630 |
| Espritz-N |
631 |
649 |
| PV2 |
632 |
646 |
| VLXT |
634 |
640 |
| IUPred-L |
636 |
640 |
| IUPred-S |
639 |
641 |
| VSL2b |
641 |
643 |
| PV2 |
656 |
656 |
| PV2 |
660 |
666 |
| PV2 |
668 |
674 |
| Espritz-N |
669 |
690 |
| PV2 |
676 |
692 |
| IUPred-L |
676 |
683 |
| VLXT |
679 |
691 |
| IUPred-S |
679 |
685 |
| VSL2b |
687 |
692 |
| PrDOS |
687 |
697 |
| IUPred-S |
688 |
688 |
| PV2 |
694 |
698 |
| VSL2b |
695 |
697 |
| VSL2b |
699 |
719 |
| PrDOS |
702 |
719 |
| PV2 |
703 |
719 |
| VLXT |
709 |
719 |
| IUPred-S |
709 |
709 |
| Espritz-X |
709 |
719 |
| IUPred-S |
711 |
719 |
| Espritz-N |
711 |
719 |
SCOP Domain Regions
Hits with strong support:
| Superfamily Name |
SFam ID |
SFam E-value |
Family Name |
Fam ID |
Fam E-value |
Region |
| PAP/OAS1 substrate-binding domain |
81631 |
2.25e-53 |
2'-5'-oligoadenylate synthetase 1, OAS1, second domain |
101271 |
0.0000303 |
193-335 |
| Nucleotidyltransferase |
81301 |
3.6e-59 |
2'-5'-oligoadenylate synthetase 1, OAS1, N-terminal domain |
102937 |
0.00000999 |
339-535 |
| PAP/OAS1 substrate-binding domain |
81631 |
4.19e-63 |
2'-5'-oligoadenylate synthetase 1, OAS1, second domain |
101271 |
0.00000401 |
536-682 |
| Nucleotidyltransferase |
81301 |
2.83e-49 |
|
|
|
8-192 |
Hits with weaker support:
No weak SCOP hits found.
Pfam Domain Regions
| Type |
Clan |
Family |
Name |
Description |
E-value |
Bitscore |
Start |
End |
| Domain |
No Clan |
PF10421.4 |
OAS1_C |
2'-5'-oligoadenylate synthetase 1, domain 2, C-terminus |
6.7e-75 |
250.7 |
152 |
339 |
| Pfam-B |
No Clan |
PB001176 |
|
|
0.0000014 |
27.4 |
364 |
453 |
| Family |
CL0260 |
PF01909.18 |
NTP_transf_2 |
Nucleotidyltransferase domain |
0.0000023 |
27.8 |
373 |
475 |
| Domain |
No Clan |
PF10421.4 |
OAS1_C |
2'-5'-oligoadenylate synthetase 1, domain 2, C-terminus |
6.9e-85 |
283.3 |
495 |
686 |
Post Translational Modification Sites
| Locus |
Amino Acid |
Disordered |
PTM Type |
Sequence Context |
| 2 |
G |
Yes |
MYRISTOYLATION |
GNGESQLSSV |
| 134 |
K |
No |
UBIQUITYLATION |
FTIQVFTkNQRISFE |
| 169 |
K |
Yes |
UBIQUITYLATION |
ELKRSLDkTNASPGE |
| 250 |
T |
No |
PHOSPHORYLATION |
DIAEGVRtVLELIKC |
| 360 |
K |
No |
ACETYLATION |
KEFLQPNkCFLEQID |
| 360 |
K |
No |
UBIQUITYLATION |
KEFLQPNkCFLEQID |
| 378 |
K |
No |
ACETYLATION |
NIIRTFLkENCFRQS |
| 378 |
K |
No |
UBIQUITYLATION |
NIIRTFLkENCFRQS |
| 417 |
S |
No |
PHOSPHORYLATION |
DLVVFHNsLKSYTsQ |
| 423 |
S |
Yes |
PHOSPHORYLATION |
NsLKSYTsQkNERHK |
| 425 |
K |
Yes |
UBIQUITYLATION |
LKSYTsQkNERHKIV |
| 433 |
K |
Yes |
ACETYLATION |
NERHKIVkEIHEQLk |
| 440 |
K |
Yes |
UBIQUITYLATION |
kEIHEQLkAFWREKE |
| 466 |
S |
Yes |
PHOSPHORYLATION |
WKAPRVLsFSLKSkV |
| 472 |
K |
Yes |
UBIQUITYLATION |
LsFSLKSkVLNESVS |